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Drug Discovery and Development Vol. 2: Drug Development Ed by Mukund S. Chorghade

Contributor(s): Chorghade, Mukund S [Editor].
Material type: materialTypeLabelBookPublisher: New Jersey John Wiley & Sons Inc. 2006Description: 381p.ISBN: 9780471398479.Subject(s): Drug Development | Drug DiscoveryDDC classification: 615.19
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Book Book Institute of Pharmacy
Reference 615.19 DRU (Browse shelf) Not For Loan P0004967
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This two volume set provides a comprehensive account of the entire sequence of operations involved in discovering a drug through the actual delivery of the drug to clinicians and medical practitioners. Includes case studies of the discovery of erythromycin analogs (antibiotics), Tagamet, and Ultiva (remifentanil).Discusses the discovery of agents for the treatment and management of bacterial infections, Parkinson's disease, psoriasis, ulcers and stomach pain, atopic dermatitis, asthma, and cancer.Contains chapters on combinatorial chemistry, molecular biology-based drug discovery, genomics, and chemogenomics.The first volume of this set thoroughly describes conceptualizing a drug, creating a library of candidates for testing, screening those candidates for in vitro and in vivo activity, conducting and analyzing the results of clinical trials, and revising the drug as necessary.

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