Computational Toxicology: Risk Assessment for Pharmaceutical and Environmental Chemicals (Record no. 15299)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01916nam a2200169Ia 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 140223b2007 xxu||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780470049624 |
| Terms of availability | 0.00 |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.9001 |
| Item number | COM |
| 245 ## - TITLE STATEMENT | |
| Title | Computational Toxicology: Risk Assessment for Pharmaceutical and Environmental Chemicals |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc | New Jersey |
| Name of publisher, distributor, etc | John Wiley & Sons Inc. |
| Date of publication, distribution, etc | 2007 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 814p |
| 500 ## - GENERAL NOTE | |
| General note | A comprehensive analysis of state-of-the-art molecular modeling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicals.This unique volume describes how the interaction of molecules with toxicologically relevant targets can be predicted using computer-based tools utilizing X-ray crystal structures or homology, receptor, pharmacophore, and quantitative structure activity relationship (QSAR) models of human proteins. It covers the in vitro models used, newer technologies, and regulatory aspects. The book offers a complete systems perspective to risk assessment prediction, discussing experimental and computational approaches in detail, with:An introduction to toxicology methods and an explanation of computational methods,In-depth reviews of QSAR methods applied to enzymes, transporters, nuclear receptors, and ion channels, Sections on applying computers to toxicology assessment in the pharmaceutical industry and in the environmental arena, Chapters written by leading international experts, Figures that illustrate computational models and references for further information, This is a key resource for toxicologists and scientists in the pharmaceutical industry and environmental sciences as well as researchers involved in ADMET, drug discovery, and technology and software development. |
| 600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME | |
| Personal name | Toxicology |
| 9 (RLIN) | 4977 |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ekins, Sean |
| Relator term | Editor |
| 9 (RLIN) | 17127 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Item type | Book |
| Call number prefix | 615.9001 |
| Call number suffix | COM |
| 995 ## - RECOMMENDATION 995 [LOCAL, UNIMARC FRANCE] | |
| Origin of item (home branch) (free text) | Pharmacy Reference |
| Genre | P0005178 |
| Section | 615.9001 |
| Recipient parent organisation code | P0005178 |
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