Delivery Technology for Biopharmaceuticals: Peptides, Proteins, Nucleic Acids and Vaccines (Record no. 15332)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02328nam a2200169Ia 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 140223b2010 xxu||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780470723388 |
| Terms of availability | 0.00 |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.6 |
| Item number | DEL |
| 245 ## - TITLE STATEMENT | |
| Title | Delivery Technology for Biopharmaceuticals: Peptides, Proteins, Nucleic Acids and Vaccines |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc | New Jersey |
| Name of publisher, distributor, etc | John and Wiley Sons, Inc. |
| Date of publication, distribution, etc | 2010 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 421p |
| 500 ## - GENERAL NOTE | |
| General note | Advances in biotechnology have provided scientists with an increasing number of biopharmaceuticals such as novel peptide and protein drugs as well as nucleic acid based drugs for gene therapy. However, successful delivery of these biopharmaceuticals is a major challenge because their molecular properties lead to poor physical and chemical stability in the body and limited membrane permeability. Therefore researchers are developing a range of new delivery technologies and materials to enable these new drugs to be delivered intact to their target sites.Delivery Technologies for Biopharmaceuticals describes strategies to overcome the main barriers for successful delivery of therapeutic peptides, proteins, and nucleic acid-based drugs or vaccines related to the site of administration and the target site. Many of the approaches described are reported in formulations in current clinical trials as well as in marketed products. Contents include: * challenges in delivery of biopharmaceuticals * novel formulation approaches for peptide and protein injectables * non-viral chemical vectors and viral technology for delivery of nucleic acid based drugs * immune response, adjuvants and delivery systems for vaccines * several examples of delivery systems for different biopharmaceuticals * a critical assessment of delivery technologies for biopharmaceuticals Delivery Technologies for Biopharmaceuticals is an essential single-volume introduction to the technologies used by researchers to ensure efficient delivery of this exciting new class of drugs. It will be of value to researchers and students working in drug delivery, formulation, biopharmaceuticals, medicinal chemistry, and new materials development. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Neilson, Hanne Morck |
| Relator term | Editor |
| 9 (RLIN) | 108306 |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jorgensen, Lene |
| Relator term | Editor |
| 9 (RLIN) | 108307 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Item type | Book |
| 995 ## - RECOMMENDATION 995 [LOCAL, UNIMARC FRANCE] | |
| Origin of item (home branch) (free text) | Pharmacy Reference |
| Genre | P0007371 |
| Section | 615.6 |
| Recipient parent organisation code | P0007371 |
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