NMR Spectroscopy in Pharmaceutical Analysis (Record no. 15926)

MARC details
000 -LEADER
fixed length control field 02167nam a2200193Ia 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 140223b2008 xxu||||| |||| 00| 0 eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9780444531735
Terms of availability 0.00
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 547
Item number NMR
245 ## - TITLE STATEMENT
Title NMR Spectroscopy in Pharmaceutical Analysis
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc Amsterdam
Name of publisher, distributor, etc Elsevier
Date of publication, distribution, etc 2008
300 ## - PHYSICAL DESCRIPTION
Extent 501p
500 ## - GENERAL NOTE
General note For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples. Combines theory, techniques, and concrete applications-all of which closely resemble the laboratory experience . considers international pharmacopoeias, addressing the concern for licensing . features the work of academics and researchers, appealing to a broad readership
600 ## - SUBJECT ADDED ENTRY--PERSONAL NAME
Personal name Spectroscopy
9 (RLIN) 109064
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Holzgrabe, Ulrike
Relator term Editor
9 (RLIN) 109065
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Wawer, Iwona
Relator term Editor
9 (RLIN) 109066
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Diehl, Bernd
Relator term Editor
9 (RLIN) 109067
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Item type Book
995 ## - RECOMMENDATION 995 [LOCAL, UNIMARC FRANCE]
Origin of item (home branch) (free text) Pharmacy Reference
Genre P0006519
Section 547
Recipient parent organisation code P0006519

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