Investigation on Antibactarial Activity of Certain Natural Products (Record no. 20687)

MARC details
000 -LEADER
fixed length control field 02014ngm a2200169Ia 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 140223b2009 xxu||||| |||| 00| 0 eng d
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 572
Item number DES
245 ## - TITLE STATEMENT
Title Investigation on Antibactarial Activity of Certain Natural Products
Statement of responsibility, etc by Komal Desai, Dhara Patel, Deepmala Lawani
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc Ahmedabad
Name of publisher, distributor, etc Institute of Science, Nirma University
Date of publication, distribution, etc 2009
300 ## - PHYSICAL DESCRIPTION
Extent 97p
500 ## - GENERAL NOTE
General note ABSTRACT Seed extracts of three different plants viz. Phoenix sylvestris, Tricosanthes dioica, and Syzygium cumini were screened for their antibacterial activity against various pathogenic bacteria. Extracts were prepared by microwave assisted extraction (MAE) method. Antibacterial activity of the seed extracts was investigated against nine bacterial strains by disc diffusion assay (DDA). Minimum inhibitory concentration (MIC) of potent extracts were also determined by broth dilution assay. The highest antibacterial potential was observed with ethanol extract of S. cumini seeds which inhibited 78% of tested microorganisms. Amongst the microorganisms tested, the most resistant was found to be Aeromonas hydrophila and the most susceptible was Salmonella paratyphi A. The phytochemical analysis of ethanol extract of S. cumini and P. sylvestris seeds revealed the presence of phenols, flavones, and alkaloids. The phytoconstituents of methanol extract of S. cumini seeds were separated by means of thin-layer chromatography (TLC). DDA of separated components was carried out and antibacterial activity was found in components having Rf value 0.59 and 0.52. Synergistic activity between these components was not observed. From this study it can be said that further investigation of methanol and ethanol extracts of S. cumini seeds and ethanol extract of P. sylvestris seeds can lead to development of novel antibacterial compound(s).
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Desai, Komal
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Lawani, Deepmala
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Patel, Dhara
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Dissertation
995 ## - RECOMMENDATION 995 [LOCAL, UNIMARC FRANCE]
Origin of item (home branch) (free text) Science Dissertation
Genre SDR00073
Section 572
Recipient parent organisation code SDR00073

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