TY  - BOOK
AU  - Krishna, Rajesh
TI  - Dose Optimization in Drug Development
SN  - 9781574448085
U1  - 615.19 
PY  - 2006///
CY  - London
PB  - Informa Healthcare
KW  - Drug Development
N1  - This reference provides a concise overview of the key principles in dose selection and optimization and demonstrates applicability to recent successful new drug applications. Compiling key issues and current research on safety, efficacy, and clinical pharmacology, and PK-PD, this volume critically highlights the multidisciplinary nature of drug development and spans the fields of pharmacokinetics, clinical pharmacology, biostatistics, and experimental medicine
ER  -