Annual Reviews of Biochemistry Vol. 68

It all Started on a Streetcar in Boston Catalysis by Metal - Activated Hydroxide in Zinc Conus Peptides Targeted to Specific Nicotinic Inorganic Polyphosphate: A Molecular of Many Functions The Molecular Basis of Hypertension Sterols and Isoprenoids: Signaling Molecules Derived From the Cholesterol Biosynthetic Pathway Ciliate Telomerase Biochemistry Tolerance and Specificity of Polyketide Synthases Initiation of Base Excision Repair: Glycosylase Mechanisms and Stuctures Structural Motifs in RNA Transcription Elongation and Human Disease Control of Carpel and Fruit Development Amino Acid Mammalian Caspases: Structure, Activation, Substrates and Functions during Apoptosis Cellular and Molecular Biology of the Aquaporin Water Channels Regulation of the Cytoskeleton and Cell Adhision By the RHo Family GTPases in MAmmalian Cells Mutagenesis of Glycosidases Charing the Fate of the GOOD CHOLESTROL Identification and Characterization of the High - Density Liproprotein Receptor SR - B Nuclear - Receptor Ligands - Building Domains The Anaphase - Promoting Complex: New Subunits and Regulators In vitro selection of Functional Nucleic Acids MCM Proteins in DNA Replication Structural Mechanism of Muscle Contraction Functions of Cell Surface Heparan Sulfate Proteoglycans De Novo Design and Structural Characterization of Proteins and Metalloproteins CREB: A Stimulus - Induced Transcription Factor Activated by a Diverse Array of Extrscellular Signals Membrane Fusion and Exocytosis EIF4 Initiation Factors: Effectors of mRNA Recruitment to Ribosomes and Regulators of Translation AKT/PKB and other D3 Phosphoinositide - Regulated Kinases: Kinase Activation by Phosphoinositide Dependent Phosphorylation The 26S Proteasome: A Molecular Machine Disigned for Controlled Proteolysis