Molecular Carcinogenesis and the Molecular Biology of Human Cancer

Carcinogens and mutagens p. 1 Whole animal carcinogenicity bioassays p. 25 Molecular mechanisms of action of selected organic carcinogens p. 45 Binding of carcinogens to DNA and covalent adducts and DNA damage - PAH, aromatic amines, nitro-aromatic compounds, and halogenated compounds p. 79 Cellular oncogenes and carcinogenesis p. 103 Tumor suppressor genes p. 131 Hepatitis B, hepatitis C, and hepatocellular carcinoma p. 151 Oncongenesis in transgenic and knockout mice p. 179 Chemically induced morphological and neoplastic transformation in C3H/10T1/2 Cl 8. mouse embryo cells p. 199 Radiation carcinogenesis p. 221 DNA microarrays and computational analysis of DNA microarray data in cancer research p. 243 Application of proteomics in basic biological sciences and cancer p. 263 Overview of human cancer induction and human exposure to carcinogens p. 289 Complex mixtures of chemical carcinogens : principles of action and human cancer p. 303 Lung cancer p. 319 Breast cancer p. 341 Cancer of the prostate - mechanisms of molecular carcinogenesis p. 363 Skin cancer : epidemiology, clinical manifestations, and genetic and molecular aspects p. 379 Cell and molecular biology of cancer of the brain p. 403 Thyroid cancer : molecular biology and clinical aspects p. 431 Chemoprevention of chemical carcinogenesis and human cancer p. 445 Carcinogen biomarkers and exposure assessment p. 479 Risk assessment for chemical carcinogens p. 501 Prevention and regulation approaches to carcinogens p. 547