000			01498nam a2200193Ia 4500
008			140223b1997 xxu||||| |||| 00| 0 eng d
020			_a9780841234819 _c0.00
082			_a615.7 _bWEL
100			_aWelling, Peter G. _916835
245			_aPharmacokinetics: Processes, Mathematics, and Applications
250			_a2nd ed
260			_aWashington _bAmerican Chemical Society Publication _c1997
300			_a393p
500			_aPharmacokinetics is the study of the absorption, distribution, metabolism, and excretion of drugs in humans. This book, written by an internationally known researcher, teaches the basic principles, including drug transport, parenteral and enteral routes of drug administration, and factors affecting drug absorption, distribution, and metabolism. Extensively revised, this edition presents the mathematics of pharmacokinetics with various single- and multi-compartment models including detailed descriptions of metabolite and nonlinear pharmacokinetics. It also describes renal and hepatic drug clearance, and the influence of kidney and liver impairment on these functions. Taking a tutorial approach throughout, the author provides both a clear introduction to pharmacokinetics and a critical look at how this science affects drug discovery and development.
600			_aPharmacokinetics _918136
942			_2ddc _cLB _k615.7 _mWEL
995			_aPharmacy Lending _eP0002878 _j615.7 _yP0002878
995			_aPharmacy Reference _eP0005541 _j615.7 _yP0005541
999			_c13843 _d13843