000			02052nam a2200157Ia 4500
008			140223b2010 xxu||||| |||| 00| 0 eng d
020			_a9781420067583 _c0.00
082			_a615.7 _bCHO
245			_aAdvances in Chromatographic Techniques for Therapeutic Drug Monitoring
260			_aLondon _bCRC Press _c2010
300			_a455p
500			_aFor drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for implementing preferred gas and liquid chromatographic methods, Advances in Chromatographic Techniques for Therapeutic Drug Monitoring is a comprehensive reference describing the theory and application of therapeutic drug monitoring in clinical laboratories. Edited by a distinguished authority in the field and containing contributions from a variety of experts, the book discusses preanalytical variables, the pitfalls of immunoassays, tandem mass spectrometry, issues related to pain management and herbal supplements, and therapeutic drug monitoring for a range of medications, including: * Anticonvulsants * Digitalis * Cardioactive drugs * Antidepressants * Immunosuppressants * Anti-cancer drugs * Vancomycin and aminoglycosides * Antibiotics * Antiretroviral drugs * Nonnarcotic analgesics * Anti-inflammatory drugs Examing older and newer drugs, the book contains detailed discussions on the rationale for therapeutic drug monitoring of each class of drugs, along with their basic pharmacology and toxicology. An extensive list of references is provided at the end of each chapter so that those interested in implementing a new drug assay can find the most appropriate method for the intended drug.
700			_aDasgupta, Amitava _eEditor _9108091
942			_2ddc _cLB
995			_aPharmacy Reference _eP0007335 _j615.7 _yP0007335
999			_c15005 _d15005