000			03708nam a2200169Ia 4500
008			140223b2003 xxu||||| |||| 00| 0 eng d
020			_a9783527306329 _c0.00
082			_a615.19 _bCAR
100			_aWong, Chi-Huey
245			_aCarbohydrate-based Drug Discovery Vol.I
260			_aWeinheim _bWiley-VCH Verlag Gmbh _c2003
300			_a459p
500			_aThis handbook presents the latest knowledge on carbohydrate chemistry and biochemistry so as to exploit the full potential of this diverse compound class for the development of novel active substances. While it is unique in covering the entire field, particular emphasis is placed on carbohydrates with pharmaceutical potential. Topics include the following: * Chemical synthesis of carbohydrates * Carbohydrate biosynthesis and metabolism * Carbohydrate analysis * Cellular functions of carbohydrates * Development of carbohydrate-based drugs A premier resource for carbohydrate chemists and drug developers, this comprehensive two-volume work contains contributions by more than 50 of the world's leading carbohydrate chemists. About the Author Professor Chi-Huey Wong received his B.S. and M.S. degrees from National Taiwan University, and Ph.D. in Chemistry (with George Whitesides) from Massachusetts Institute of Technology in 1982. He started his independent career as Assistant Professor of Chemistry at Texas A&M University in 1983, where he became Full Professor in 1987. He has been Professor and Ernest W. Hahn Chair in Chemistry at the Scripps Research Institute since 1989 and is also a member of the Skaggs Institute for Chemical Biology since 1996. Professor Wong is a member of the U.S. National Academy of Sciences and the American Academy of Arts and Sciences. He is a recipient of The Searle Scholar Award in Biomedical Sciences (1985), the Presidential Young Investigator Award in Chemistry (1986), the American Chemical Society A.C. Cope Scholar Award (1993), the Roy Whistler Award of the International Carbohydrate Organization (1994), the American Chemical Society Harrison Howe Award in Chemistry (1998) and the Claude S. Hudson Award in Carbohydrate Chemistry (1999), the International Enzyme Engineering Award (1999) and the Presidential Green Chemistry Challenge Award (2000). He is a member of Academia Sinica, Taipei (1994), the American Academy of Arts and Sciences (1996) and the US National Academy of Sciences (2002). He serves as editor-in-chief of Bioorganic and Medicinal Chemistry and is an executive board member of the Tetrahedron Publications. He was head of the Frontier Research Program on Glycotechnology at RIKEN (Institute of Physical and Chemical Research, Japan) (1991-1999) and is currently a scientific advisor of the Max-Planck Institute, a board member of the U.S. National Research Council on Chemical Sciences and Technology, and is a founding scientist of Optimer Pharmaceuticals, Inc. He is author and co-author of over 450 publications, 60 patents and several books. His current interests are in the areas of bioorganic and synthetic chemistry and biocatalysis, including development of new synthetic chemistry based on enzymatic and chemo-enzymatic reactions, synthetic approach to carbohydrate-mediated biological recognition, design and synthesis of mechanism-based inhibitors of enzymes, RNA and carbohydrate receptors, development of oligosaccharide and aminoglycoside microarrays for high-throughput screening and the study of reaction mechanisms.
600			_aDrug Discovery
890			_aUSA
995			_ACAR _B004455 _CPHA-NIP _D10647.00 _E0 _F049 _G369 _H0 _I0.00 _L20060302 _M1 _UC _W20060317 _XViraj Marketing-p _ZReference
999			_c15183 _d15183