000 01717nam a2200193Ia 4500
008 140223b1999 xxu||||| |||| 00| 0 eng d
020 _a9780792359807
_c0.00
082 _a615.19
_bMOL
245 _aMolecular Diversity in Drug Design
260 _aNew York
_bKluwer Academic / Plenum Publishers
_c1999
300 _a253p
500 _aThis book focuses on the theoretical problems associated with molecular diversity as it is being applied in the pharmaceutical industry. Therefore, this book deals with algorithms that are involved in understanding chemical space and selection of diverse sets of structures. The algorithms also deal with the problem of focused diversity where chemical libraries are being created within a structured physical volume. Diversity is necessarily connected to combinational chemistry, although this book is limited to the application of diversity methods to combinational chemistry and does not deal with synthetic methods. It is this focus on algorithms and strategies for exploiting molecular diversity that makes it different from books on combinational chemistry. The intended readership of the book falls into two categories: those actively engaged in applying molecular diversity in the chemical industry and those in academia who are developing strategies to embrace, understand and accept the many problems thrown up by this new research field of molecular diversity.
600 _aMolecular Chemistry
_9105215
600 _aMolecular Drug Design
_9105216
700 _aDean, Philip M.
_eEditor
_9105217
700 _aLewis, Richard A.
_eEditor
_9105218
942 _2ddc
_cLB
995 _aPharmacy Reference
_eP0007721
_j615.19
_yP0007721
999 _c15887
_d15887