000			02128nam a2200193Ia 4500
008			140223b2010 xxu||||| |||| 00| 0 eng d
020			_a9781607610571 _c0.00
082			_a615.1 _bMOU
245			_aMouse Models for Drug Discovery: Methods and Protocols
260			_aNew Jersey _bHumana Press _c2010
300			_a421p
440			_aMethods in Molecular Biology Vol. 602 _9108962
500			_aAs the drug discovery process shifts more and more toward specifically targeting pathways and molecules, model systems continue to increase in importance, and the mouse, with its versatility, ease of use, and remarkable similarity to the human genome, has clearly risen to the forefront of animal model studies. In Mouse Models for Drug Discovery: Methods and Protocols, experts in the field present some background for those less familiar with mice as experimental model platforms as well as a collection of techniques involving general methods as well as specific disease topics such as type 1 and 2 diabetes, cardiovascular disease, arthritis, skin disorders, cancer, the use of behavioral models for depression and anxiety, neurodegenerative diseases, neuromuscular diseases, and infectious diseases. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easy-to-use, Mouse Models for Drug Discovery: Methods and Protocols will stimulate those not familiar with the power of the mouse and its potential for the drug discovery process, and it will encourage the development of new models and new ways to utilize existing models in order to further the use of this dynamic animal in this vital field.
600			_aDrug Discovery _9108963
700			_aProetzel, Gabriele _eEditor _9108964
700			_aWiles, Michael V. _eEditor _9108965
942			_2ddc _cLB
995			_aPharmacy Reference _eP0007370 _j615.1 _yP0007370
999			_c15893 _d15893