000			01566nam a2200181Ia 4500
008			140223b2005 xxu||||| |||| 00| 0 eng d
020			_a9781588293831 _c0.00
082			_a615.32 _bNAT
245			_aNatural Products: Drug Discovery and Therapeutic Medicine
260			_aNew Jersey _bHumana Press _c2005
300			_a382p
500			_aA fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
600			_aPharmacognosy _9105065
700			_aZhang, Lixin _eEditor _9105066
700			_aDemain, Arnold L. _eEditor _9105067
942			_2ddc _cLB
995			_aPharmacy Reference _eP0002363 _j615.32 _yP0002363
999			_c15918 _d15918