000			01870nam a2200181Ia 4500
008			140223b2003 xxu||||| |||| 00| 0 eng d
020			_a9780824741242 _c0.00
082			_a615.6 _bOPH
245			_aOphthalmic Drug Delivery Systems
250			_a2nd ed
260			_aNew York _bMarcel Dekker, Inc. _c2003
300			_a727p
500			_aExtensively revised and updated, this second edition compares conventional and innovative drug delivery systems. The book covers significant ophthalmic advances and breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery. It examines procedures in pharmacokinetic/pharmacodynamic modeling for the determination of appropriate dosing regimens, covers new developments in animal modeling, and discusses current regulations governing patenting, commercial product release, and human testing. This in-depth reference lays the groundwork for overcoming constraints on the delivery of ophthalmic drugs. fluorescein glucuronide, transcorneal iontophoresis, transscleral iontophoresis, injection displaced, compartmental shells, retinal permeability, ocular iontophoresis, pigmented rabbit conjunctiva, following topical ocular administration, ocular pharmacokinetics, intraocular entry, vitreous site, noncorneal route, conjunctival permeability, noncorneal penetration, rabbit conjunctival epithelial cells, aqueous humor volume, corneal drug penetration, following systemic drug administration, noncorneal pathway, ocular gene therapy, shields hydrated, collagen shields, collagen shield delivery, precorneal area
600			_aDrug Delivery System _912606
700			_aMitra, Ashim K. _eEditor _99010
942			_2ddc _cLB _k615.6 _mOPH
995			_aPharmacy Reference _eP0006194 _j615.6 _yP0006194
999			_c15932 _d15932