000			02485nam a2200181Ia 4500
008			140223b2000 xxu||||| |||| 00| 0 eng d
020			_a9780471331957 _c0.00
082			_a547.2 _bSEN
100			_aSeneci, Pierfausto
245			_aSolid-Phase Synthesis and Combinatorial Technologies
260			_aNew York _bWiley-Interscience _c2000
300			_a637p
500			_aA unique, integrated look at solid-phase synthesis and advances in combinatorial chemistry and technologies The last decade has seen a rapid expansion in combinatorial technologies, a field where chemistry disciplines intersect with automation, statistics, and information science, as well as certain biological disciplines. Reflecting these multidisciplinary trends, this new work provides a comprehensive overview of the most important aspects of solid-phase synthesis (SPS), combinatorial chemistry, and related combinatorial technologies. It clearly demonstrates how SPS and combinatorial chemistry have extended their application from the pharmaceutical arena to new areas, including biotechnology, material sciences, catalysis, and agrochemical industries, and explores in detail strategies for planning, designing, preparing, and testing of combinatorial libraries in various disciplines. Designed to meet the needs of both experienced combinatorial chemists and newcomers to the field, Solid-Phase Synthesis and Combinatorial Technologies: * Surveys the most recent developments in SPS and combinatorial chemistry * Explains the entire process, from determining the need for a library to the details necessary for synthesis of the library * Discusses choice of format, size, and the rationale behind the design of each synthetic step * Surveys the analytical techniques and the purification methods used to characterize and purify combinatorial libraries * Employs a large number of examples to illustrate important concepts * Includes problems geared toward applying acquired knowledge and designing the steps to SPS/library synthesis * Describes the quality control and activity screening of combinatorial libraries for various applications * Features a detailed bibliography of more than 1,700 relevant sources
600			_aOrganic Synthesis
890			_aUSA
891			_aScience & Technology - Chemistry {QuickPic}
995			_ASEN _B004364 _CPHA-NIP _D6594.00 _E0 _F049 _G131 _H0 _I0.00 _L20060216 _M1 _UC _W20060302 _XPustak _ZReference
999			_c16260 _d16260