000			01508nam a2200193Ia 4500
008			140223b2005 xxu||||| |||| 00| 0 eng d
020			_a9780781755658 _c0.00
082			_a615.724 _bSCH
100			_aSchuster, Daniel P.
245			_aTranslational and Experimental Clinical Research
260			_aPhiladelphia _bLippincott Williams & Wilkins _c2005
300			_a490p
500			_aThis volume is a comprehensive textbook for investigators entering the rapidly growing field of translational and experimental clinical research. The book offers detailed guidelines for designing and conducting a study and analyzing and reporting results and discusses key ethical and regulatory issues.Chapters address specific types of studies such as clinical experiments in small numbers of patients, pharmacokinetics and pharmacodynamics, and gene therapy and pharmacogenomic studies. A major section describes modern techniques of translational clinical research, including gene expression, identifying mutations and polymorphisms, cloning, transcriptional profiling, proteomics, cell and tissue imaging, tissue banking, evaluating substrate metabolism, and in vivo imaging.
600			_aClinical Research
600			_aMedicine
700			_aPowers, William J.
890			_aUSA
995			_ASCH _B008183 _CCOM-COL _D5009.65 _E0 _F049 _G98643 _H0 _I0.00 _J7006.50 28.5% _L20090226 _M03 _UC _W20090328 _XHimanshu Book Co. _ZReference
999			_c16359 _d16359