000			02014ngm a2200169Ia 4500
008			140223b2009 xxu||||| |||| 00| 0 eng d
082			_a572 _bDES
245			_aInvestigation on Antibactarial Activity of Certain Natural Products _cby Komal Desai, Dhara Patel, Deepmala Lawani
260			_aAhmedabad _bInstitute of Science, Nirma University _c2009
300			_a97p
500			_aABSTRACT Seed extracts of three different plants viz. Phoenix sylvestris, Tricosanthes dioica, and Syzygium cumini were screened for their antibacterial activity against various pathogenic bacteria. Extracts were prepared by microwave assisted extraction (MAE) method. Antibacterial activity of the seed extracts was investigated against nine bacterial strains by disc diffusion assay (DDA). Minimum inhibitory concentration (MIC) of potent extracts were also determined by broth dilution assay. The highest antibacterial potential was observed with ethanol extract of S. cumini seeds which inhibited 78% of tested microorganisms. Amongst the microorganisms tested, the most resistant was found to be Aeromonas hydrophila and the most susceptible was Salmonella paratyphi A. The phytochemical analysis of ethanol extract of S. cumini and P. sylvestris seeds revealed the presence of phenols, flavones, and alkaloids. The phytoconstituents of methanol extract of S. cumini seeds were separated by means of thin-layer chromatography (TLC). DDA of separated components was carried out and antibacterial activity was found in components having Rf value 0.59 and 0.52. Synergistic activity between these components was not observed. From this study it can be said that further investigation of methanol and ethanol extracts of S. cumini seeds and ethanol extract of P. sylvestris seeds can lead to development of novel antibacterial compound(s).
700			_aDesai, Komal _9121221
700			_aLawani, Deepmala _9121222
700			_aPatel, Dhara _9121223
942			_2ddc _cDIS
995			_aScience Dissertation _eSDR00073 _j572 _ySDR00073
999			_c20687 _d20687