Inhibition of Virulence Factors Controlled by Quorum Sensing in Pseudomonas Aeruginosa Using Plant Extrcts (Record no. 20679)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01524ngm a2200145Ia 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 140223b2010 xxu||||| |||| 00| 0 eng d |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 660.6 |
| Item number | BHA |
| 245 ## - TITLE STATEMENT | |
| Title | Inhibition of Virulence Factors Controlled by Quorum Sensing in Pseudomonas Aeruginosa Using Plant Extrcts |
| Statement of responsibility, etc | by Arpan, Bhatt, and Hasrajani, Vinita |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc | Ahmedabad |
| Name of publisher, distributor, etc | Institute of Science, Nirma University |
| Date of publication, distribution, etc | 2010 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 79p |
| 500 ## - GENERAL NOTE | |
| General note | ABSTRACT: Quorum sensing (QS), most commonly known as to be cell to cell signaling in bacteria, is a key regulator of virulence and biofilm formation in Pseudomonas aeruginosa and other medically relevant bacteria. In this study, five different plants of Indian origin were examined for their inhibitory effects against virulence caused by P.aeruginosa, which are under the control of Quorum sensing. The plant used are Terminalia belerica, Terminalia chebula, Vernonia anthelmintica, Nigella sativa and Moringa oleifera. Out of five plants used, T. bellerica, N. sativa and M. oleifera significantly reduced LasA and LasB activity. All five plants reduced the pyocyanin production. Additionally T. bellerica reduced the biofilm formation, which is partially regulated by QS. Plants reducing the virulence factor production marginally affect the growth of the organisms, so it suggests that anti-QS effect of plant extract is independent of any static or cidal effects. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bhatt, Arpan and Hasrajani, Vinita. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Dissertation |
| 995 ## - RECOMMENDATION 995 [LOCAL, UNIMARC FRANCE] | |
| Origin of item (home branch) (free text) | Science Dissertation |
| Genre | SDR00083 |
| Section | 660.6 |
| Recipient parent organisation code | SDR00083 |
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